KCS-content Show Comments ▼ whatsapp Miliband calls for return to industrial intervention Read This NextThe Truth About Bottled Water – Get the Facts on Drinking Bottled WaterGayotRicky Schroder Calls Foo Fighters’ Dave Grohl ‘Ignorant Punk’ forThe WrapCNN’s Brian Stelter Draws Criticism for Asking Jen Psaki: ‘What Does theThe WrapDid Donald Trump Wear His Pants Backwards? Kriss Kross Memes Have AlreadyThe WrapHarvey Weinstein to Be Extradited to California to Face Sexual AssaultThe WrapPink Floyd’s Roger Waters Denies Zuckerberg’s Request to Use Song in Ad:The Wrap’The View’: Meghan McCain Calls VP Kamala Harris a ‘Moron’ for BorderThe WrapNewsmax Rejected Matt Gaetz When Congressman ‘Reached Out’ for a JobThe Wrap2 HFPA Members Resign Citing a Culture of ‘Corruption and Verbal Abuse’The Wrap THE GOVERNMENT should take a more active role in the private sector, Ed Miliband will say today, as he warns against returning to “business as usual” in the wake of the slump. Speaking at the CBI’s annual conference, Miliband will argue that government should not shy away from pursuing a policy of industrial interventionism. “What it means to be pro-business in the 2010s is different to what it meant in the 1990s. It means more than just getting out of the way,” he is expected to say. “Government should not be afraid to provide support to business that the market will not offer. That is the way to rebalance our economy.”Miliband will also claim the government has become obsessed with spending cuts at the expense of an economic strategy, a charge the Prime Minister will try to deflect with a series of pro-growth announcements to day. And the new Labour leader will champion small businesses at the expense of big business, adopting a tone that is remarkably similar to the coalition’s. “The change Tony Blair brought to our party certainly made us more welcoming for big business, but we must do more to understand the real importance of small business.”Meanwhile, Miliband is expected to defend his stance on the deficit, which he thinks should be paid down more slowly. Share whatsapp by Taboolaby TaboolaSponsored LinksSponsored LinksPromoted LinksPromoted LinksYou May LikeMisterStoryWoman Files For Divorce After Seeing This Photo – Can You See Why?MisterStoryTotal PastThe Ingenious Reason There Are No Mosquitoes At Disney WorldTotal PastMoneyPailShe Was The Dream Girl In The 90s, This Is Her NowMoneyPailSerendipity TimesInside Coco Chanel’s Eerily Abandoned Mansion Frozen In TimeSerendipity TimesBrake For ItThe Most Worthless Cars Ever MadeBrake For ItBetterBe20 Stunning Female AthletesBetterBemoneycougar.comThis Proves The Osmonds Weren’t So Innocentmoneycougar.comTaonga: The Island FarmThe Most Relaxing Farm Game of 2021. No InstallTaonga: The Island Farmthedelite.comNetflix Cancellations And Renewals: The Full List For 2021thedelite.com Sunday 24 October 2010 10:52 pm Tags: NULL
KCS-content whatsapp AGGREKO, the Scottish power specialist, has sealed a £37m deal to supply electricity to the London 2012 Olympic Games.The Glasgow-based company will provide about 220 megawatts of power – some 60 megawatts more than it supplied at the Beijing games in 2008.Aggreko has also provided power for the football World Cup in South Africa and the Vancouver Winter Olympics.The company, which has 5,000 employees, said it had also been signed up as a sponsor for the London games after winning the deal. Monday 20 December 2010 8:06 pm Show Comments ▼ Share Aggreko wins Olympics deal Tags: NULL Read This Next’A Quiet Place Part II’ Sets Pandemic Record in Debut WeekendFamily ProofHiking Gadgets: Amazon Deals Perfect For Your Next AdventureFamily ProofIndian Spiced Vegetable Nuggets: Recipes Worth CookingFamily ProofAmazon roars for MGM’s lion, paying $8.45 billion for studio behind JamesFamily ProofYoga for Beginners: 3 Different Types of Yoga You Should TryFamily ProofBack on the Rails for Summer New York to New Orleans, Savannah and MiamiFamily ProofChicken Bao: Delicious Recipes Worth CookingFamily ProofCheese Crostini: Delicious Recipes Worth CookingFamily ProofHomemade Tomato Soup: Delicious Recipes Worth CookingFamily Proof whatsapp
Facebook Twitter Bett1Open 2021 Final: Liudmila Samsonova beat Belinda Bencic to clinch title by Taboolaby TaboolaSponsored LinksSponsored LinksPromoted LinksPromoted LinksYou May LikeGrammarlyImprove Your Spelling With This Helpful Browser ExtensionGrammarlyUndoIPL 2020: Bad news for Sunrisers Hyderabad’s Jonny BairstowUndoIPL 2020 : Srikanth and fans slams MS Dhoni, says ‘wasted 15 Cr on Jadhav & Chawla’UndoWishing one of the most destructive and entertaining T20 players, @henrygayle, a very very Happy Birthday! Have a great day Universe BOSS! #PlayBold #HappyBirthdayChrisGayle pic.twitter.com/OKJFqyYkAh— Royal Challengers Bangalore (@RCBTweets) September 21, 2020 Taking to Twitter KXIP wrote: World’s oldest Goat #SaddaPunjab #HappyBirthdayGOATWorld’s oldest @GWR, care to confirm? #SaddaPunjab #HappyBirthdayGOAT @henrygayle pic.twitter.com/RW6iAEOMqv— Kings XI Punjab (@lionsdenkxip) September 21, 2020Taking on Twitter Yuvraj Singh wrote: Happy Birthday to the #UniverseBoss @henrygayle! A legend who lives by his own rules on the pitch and in life too! Have a phenomenal day kaka Fisted hand Clinking glasses wishing you a wonderful IPL!Happy Birthday to the #UniverseBoss @henrygayle! A legend who lives by his own rules on the pitch and in life too! Have a phenomenal day kaka wishing you a wonderful IPL! pic.twitter.com/XJRRmc9kKc— Yuvraj Singh (@YUVSTRONG12) September 21, 2020Taking on Twitter Virat Kohli wrote: Wishing you a very Happy Birthday @henrygayle. Have a great year ahead.Wishing you a very Happy Birthday @henrygayle. Have a great year ahead. — Simranjeet Singh (@imVkohli) September 21, 2020 The ‘Universe Boss’ is widely regarded as one of the most dangerous batsmen in the shortest format of the game, and currently holds the record for most runs in T20 cricket.Gayle has represented 26 teams in T20 cricket, which include the West Indies, his domestic side Jamaica and the franchise sides from all around the world. Having played 404 T20 matches so far, Gayle is one of the only two batsmen (the other being Kieron Pollard) to cross 10,000-run mark in the shortest format of the game. He has scored 13,296 runs at an incredible strike-rate of 146.94. These include 22 centuries and 82 half-centuries.Highest score in IPLPlaying his third season for RCB, Gayle went berserk in the league stage game against Pune Warriors and smashed an unbeaten 175 in 2012. He reached the three-figure mark off just 30 balls and finished at a score of 175 off 66 balls as RCB scored 263/5. He still holds the records of IPL’s highest score and quickest century in T20 cricket.Click the link below for- IPL 2020 LIVE Score, Ball by Ball Commentary, IPL LIVE Streaming, IPL Schedule, IPL Result Update, IPL LIVE Linkhttps://www.insidesport.co/indian-premier-league/ TAGSIndian Premier LeagueIPL 2020IPL 2020 in UAEKings XI PunjabKXIP- Chris GayleRCB SHARE By Kunal Dhyani – September 21, 2020 YourBump15 Actors That Hollywood Banned For LifeYourBump|SponsoredSponsoredUndoPost FunThese Twins Were Named “Most Beautiful In The World,” Wait Until You See Them TodayPost Fun|SponsoredSponsoredUndoDefinitionTime Was Not Kind To These 28 CelebritiesDefinition|SponsoredSponsoredUndoDaily FunnyFemale Athlete Fails You Can’t Look Away FromDaily Funny|SponsoredSponsoredUndoMaternity WeekA Letter From The Devil Written By A Possessed Nun In 1676 Has Been TranslatedMaternity Week|SponsoredSponsoredUndoDefinitionMost Embarrassing Mistakes Ever Made In HistoryDefinition|SponsoredSponsoredUndo RELATED ARTICLESMORE FROM AUTHOR Cricket IPL 2020: Happy Birthday Chris Gayle! From RCB to KXIP, wishes pour in for the ‘Universe Boss’ PSL 2021 Playoffs LIVE – How to watch Pakistan Super League Playoffs Live Streaming on your Mobile, Laptop Previous articlePremier League LIVE: Aston Villa vs Sheffield United LIVE in Premier League, watch live streaming on Disney+ HotstarNext articleIPL 2020 : After victory over Mumbai, CSK back as favorite to win IPL 2020 for the betting market Kunal DhyaniSports Tech enthusiast, he reports on Sports Tech industry and writes on sports products. Esports Share on Facebook Tweet on Twitter WTC Final: Sunil Gavaskar reacts to Ajinkya Rahane dismissal says, ‘Only explanation is that he was going for his fifty’ Euro 2020, Italy vs Wales LIVE: Italy kick-off proceedings in Rome; Follow Live Updates, Sport News Cricket Cricket WTC Final Day 3 LIVE Score: Latham, Conway frustrate India bowlers; NZ 60/0 (31 ovs)- Follow Live Updates CricketIndian premier leagueIndian premier league 2020SportSport News Football Football Euro 2020, Switzerland vs Turkey LIVE: Must-win game for both teams, Kickoff at 9.30PM IST; Follow Live Updates KXIP’s Chris Gayle, who is famously known as the ‘Universe Boss’, turned 41 on Monday, September 21 and birthday wishes are pouring in from all around the world, from IPL franchises to his Indian friends, Virat Kohli and Yuvraj Singh.Taking to Twitter RCB wrote: Wishing one of the most destructive and entertaining T20 players, @henrygayle, a very very Happy Birthday! Have a great day Universe BOSS PSL 2021 Playoffs Live: How to watch PSL 2021 Playoffs LIVE streaming in your country, India Cricket PUBG Mobile – Krafton IPO: PUBG Mobile promoters Krafton ready to break all records, aims 5 billion IPO Football Wimbledon 2021 LIVE streaming: When, where and how to watch year’s third Grand Slam’ in you country, India Cricket PSL 2021 Playoffs: Schedule, Timing, LIVE streaming, list of champions; all you need to know
Real Estate Investments Zambia PLC (REIZ.zm) listed on the Lusaka Securities Exchange under the Property sector has released it’s 2012 annual report.For more information about Real Estate Investments Zambia PLC (REIZ.zm) reports, abridged reports, interim earnings results and earnings presentations, visit the Real Estate Investments Zambia PLC (REIZ.zm) company page on AfricanFinancials.Document: Real Estate Investments Zambia PLC (REIZ.zm) 2012 annual report.Company ProfileReal Estate Investments Zambia PLC (REIZ), listed on the Lusaka Securities Exchange (LuSE), is the leading real estate investment, development and management company in Zambia. Originally the North Western Rhodesia Farmers Co-operative in the 1920’s, secured the current location of Central Park on Cairo Road as a collection centre for farming produce. The Co-op went through various guises until after independence in 1964 when it was renamed the Zambian Farmers Co-operative. The construction of the Farmers House building was completed in the 1970’s, hence the name by which that property became known.
Zenith Bank PLC (ZENITH.ng) listed on the Nigerian Stock Exchange under the Banking sector has released it’s 2017 interim results for the half year.For more information about Zenith Bank PLC (ZENITH.ng) reports, abridged reports, interim earnings results and earnings presentations, visit the Zenith Bank PLC (ZENITH.ng) company page on AfricanFinancials.Document: Zenith Bank PLC (ZENITH.ng) 2017 interim results for the half year.Company ProfileZenith Bank Plc is a financial services institution in Nigeria offering banking products and services for the personal, commercial, corporate, private and investment banking sectors. The company also offers non-banking services such as foreign exchange, treasury, trade services and cash management services. Its full-service offering ranges from transactional accounts, savings accounts and deposits to short term investment funds, association accounts, personal funds management, funds transfer service and import letters of credit. Established in 1990 and formerly known as Zenith International Bank Limited, the company changed its name to Zenith Bank Plc in 2004. The company has three subsidiaries: Zenith Bank (Ghana) Limited and Zenith Bank (Sierra Leone) and Zenith Bank (Gambia) Limited. It has representative offices in South Africa and The People’s Republic of China. Its company head office is in Lagos, Nigeria. Zenith Bank Plc is listed on the Nigerian Stock Exchange
LATEST RUGBY WORLD MAGAZINE SUBSCRIPTION DEALS Two months ago this column wondered if Racing 92’s season could get any worse after Johan Goosen’s retirement, the corticosteroids saga and their humiliating exit from the Champions Cup. It could, and it has. First Dan Carter was caught drink-driving on the Champs-Élysées and then his former All Black teammate, Ali Williams, was arrested for buying cocaine on the same street.The antics of the two Kiwis encapsulate the nightmarish season that 2016-17 has become for Racing president Jacky Lorenzetti. Speaking after Carter’s offence, but before Williams’, he said he felt like a “punch ball”. His mood won’t have improved after watching Racing lose away at relegation-threatened Grenoble on Saturday evening, a defeat that was inevitable once Chris Masoe – yes, another Kiwi – was dismissed after five minutes for a high tackle.Spot of bother: Dan Carter has struggled on field and off it this seasonThat result leaves Racing in seventh position, still in with a good chance of qualifying for the play-offs, but only eights points ahead of Lyon, in 12th.What must be causing Lorenzetti sleepless nights is the thought of failing to qualify for next season’s Champions Cup. He moves his club into their new stadium this summer and he needs the allure of Europe’s showpiece competition to put bums on seats and help pay some of the reported €400m construction costs.But how much has Lorenzetti brought his troubles on himself? One man who might not have much sympathy for the Racing president’s predicament is the club’s former manager, Arnaud Tourtoulou. He was relieved of his duties in June last year, the Monday after Racing had beaten Toulon to win their first Top 14 title in 26 years. Tourtoulou joined Racing in 2011 after a spell as president of Bourgoin, and was described by one French rugby writer as “an important cog…the buffer between the sporting and administration factions”. The official reason for Tourtoulou’s departure was that his contract had expired but some suspect there was more to it than that It has been a season to forget for Racing 92, with their league form patchy, a poor showing in Europe and problems with their superstar imports Plenty to ponder: Jacky Lorenzetti has invested huge resources into Racing 92Whatever the circumstances behind Tourtoulou’s exit from Racing, his role, according to an article in last week’s L’Equipe, has been filled by people from Foncia, the property management company that Lorenzetti founded more than 40 years ago, and who, according to the newspaper, are “not necessarily au fait with rugby’s customs”.Then again it’s no-one’s responsibility but the players’ to ensure they don’t get behind the wheel when they’ve been drinking or to go looking for drugs on a night out. Similarly, L’Equipe has alleged that a group of players enjoyed a night of great revelry at a Parisian restaurant just two days before a Champions Cup fixture this season.The players involved were said to be from Racing’s foreign contingent and the paper claimed a that source within the dressing room had talked of a “fracture” between the French players and the overseas ones, more specifically “the New Zealanders”. Trouble ahead: The Racing 92 players look dejected after their loss to Brive Masterclass: Finn Russell was a part of a Glasgow team that dismantled the ParisiensThis what wasn’t Lorenzetti envisaged when he signed Carter on a three year deal after the 2015 Rugby World Cup with the Kiwi pocketing a salary of £1.3 million a season. He had visions of Carter bringing to Racing the same success that Jonny Wilkinson delivered to Toulon, True, Carter played his part in the Top 14 triumph but this season he’s looked a shadow of that player, to the point where in Racing’s 23-7 defeat to Glasgow he made no carries, no metres, beat no defenders and managed no offloads.Last season Carter won fourteen of the eighteen matches he played for Racing, a figure that has fallen in 2016-17 to five wins in fourteen matches. He’s been sidelined in recent weeks with a groin injury but is expected to return for Saturday’s match at home to league leaders La Rochelle. The week after the Parisians travel to Montpellier and then they host Clermont. It’s a trio of matches that will test Racing and Carter, who, for the first time in his career is enduring sustained negative press. It’s a novel experience, as is playing in a struggling team. How Carter reacts will be fascinating.
News to go further News A court in the Baku district of Sabayil released Mehman Huseynov provisionally on the evening of 13 June but ordered him tried on charges of hooliganism and resisting the authorities under article 221.2.2 of the criminal code. The charges carry a possible five-year jail term.These are more serious that the charges originally cited. The court also placed Huseynov under judicial control pending trial.——–13.06.2012 – Outspoken photojournalist arrestedReporters Without Borders condemns the young photojournalist Mehman Huseynov’s detention since yesterday evening on a charge of hooliganism and “insulting and using force” against a member of the special forces when an opposition demonstration was dispersed in Baku on 21 May, on the eve of the Eurovision Song Contest semi-finals.A member of the Institute for Reporters’ Freedom and Safety (IRFS), Huseynov is well known for his coverage of police violence and his defence of freedom of information. He is also active on social networks and his YouTube account is closely followed.“Huseynov’s arrest bears all the hallmarks of an act of political revenge and intimidation,” Reporters Without Borders said. “He must be freed at once. “The cynicism of the charges is intolerable as it was the police who prevented him from covering the demonstration. Now that the Eurovision Song Contest is over, the authorities are beginning to make civil society pay for the protests it staged. The international community’s support is needed more than ever.”After being taken to the Sabayil district police station in Baku at around 6 p.m. yesterday, Huseynov was questioned for three hours and then placed in police custody. During the next 48 hours, a judge must rule on the charges and decide whether he will remain in pre-trial detention. A charge of hooliganism carries a possible one-year jail sentence under article 221.1 of the criminal code.Force was used against both journalists and protesters and many activists were arrested when the police broke up the 21 May demonstration in Fountains Square in Baku. Huseynov was manhandled and his camera was broken, which prompted an argument with a police officer.Huseynov is regarded as one of the leading sources of coverage of demonstrations and his work was particularly visible during the Eurovision Song Contest, when the international media made reference to Azerbaijan’s massive human rights violations. He is the brother of the head of the IRFS, Emin Huseynov.Since the end of the Eurovision Song Contest, the authorities have made it clear they intend to reassert their control. As well as arresting Huseynov and imposing a two-year jail sentence on fellow journalist Anar Bayramli, the authorities have also arrested opposition activists and a human rights defender in the past few days.Parliament meanwhile today adopted an amendment drastically restricting access to state-held information while President Ilham Aliev’s leading adviser, Ali Hasanov, appealed on 31 May for “public hatred” towards media that criticize the government and said that “opposition members of this kind, journalists and newspapers, should not dare to set a step outside!” RSF_en AzerbaijanEurope – Central Asia Follow the news on Azerbaijan June 8, 2021 Find out more June 18, 2012 – Updated on February 2, 2018 Photographer freed but now facing possible five-year jail sentence Help by sharing this information Receive email alerts RSF calls for a fully transparent investigation after mine kills two journalists in Azerbaijan April 9, 2021 Find out more News News “We’ll hold Ilham Aliyev personally responsible if anything happens to this blogger in France” RSF says June 4, 2021 Find out more Russian peacekeepers deny foreign reporters access to Nagorno-Karabakh Organisation AzerbaijanEurope – Central Asia
By Digital AIM Web Support – February 17, 2021 EU hails deals to get more vaccine shots, tackle variants Local NewsBusinessUS NewsWorld News Pinterest Facebook WhatsApp Pinterest Twitter TAGS Facebook WhatsApp Interior view of a new coronavirus, COVID-19, vaccination center at the ‘Velodrom’ (velodrome-stadium) in Berlin, Germany, Wednesday, Feb. 17, 2021. Twitter Previous articleArctaris Funds Broadband Fiber in Opportunity Zones to Increase Digital EquityNext articleESSENCE March+April Triple Cover Features Star-Studded Cast of the Highly-Anticipated Coming 2 America – Including Eddie Murphy, Arsenio Hall, Jermaine Fowler, Kiki Layne and Bella Murphy Digital AIM Web Support
Facebook Jasper Therapeutics Announces Positive Data from Phase 1 Clinical Trial of JSP191 as Targeted Stem Cell Conditioning Agent in Patients with Myelodysplastic Syndromes or Acute Myeloid Leukemia Undergoing Hematopoietic Cell Transplantation REDWOOD CITY, Calif.–(BUSINESS WIRE)–Feb 8, 2021– Jasper Therapeutics, Inc., a biotechnology company focused on hematopoietic cell transplant therapies, today announced positive preliminary findings from its ongoing multicenter Phase 1 clinical trial of JSP191, a first-in-class anti-CD117 (stem cell factor receptor) monoclonal antibody, as a conditioning agent in older patients with myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML) undergoing hematopoietic (blood) cell transplantation. Data from the first six patients who received a single dose of JSP191 prior to transplantation showed successful engraftment in all six patients. Complete donor myeloid chimerism (equal or greater than 95%) was observed in five of six evaluable patients at 28 days, and all three evaluable patients had total donor chimerism equal or greater than 95% observed at day 90. In addition, at 28 days, three of five evaluable patients showed complete eradication of measurable residual disease (MRD) as measured by next-generation sequencing. Two of the five evaluable patients showed substantial reductions in MRD. No treatment-related serious adverse events were reported. The findings were presented by lead investigator Lori Muffly, M.D., M.S., Assistant Professor of Medicine (Blood and Bone Marrow Transplantation) at Stanford Medicine, as a late-breaking abstract at the 2021 Transplantation & Cellular Therapy (TCT) Meetings of the American Society for Transplantation and Cellular Therapy (ASTCT) and the Center for International Blood & Marrow Transplant Research (CIBMTR). “These early clinical results are the first to demonstrate that JSP191 administered in combination with a standard non-myeloablative regimen of low-dose radiation and fludarabine is well tolerated and can clear measurable residual disease in older adults with MDS or AML undergoing hematopoietic cell transplantation – a patient population with historically few options,” said Kevin N. Heller, M.D., Executive Vice President, Research and Development, of Jasper Therapeutics. “These patients could be cured by hematopoietic cell transplantation, but the standard-of-care myeloablative conditioning regimens used today are highly toxic and associated with high rates of morbidity and mortality particularly in older adults. Traditional lower intensity transplant conditioning regimens are better tolerated in older adults, but are associated with higher rates of relapse in MDS/AML patients with measurable residual disease. JSP191, a well-tolerated biologic conditioning agent that targets and depletes both normal hematopoietic stem cells and those that initiate MDS and AML, has the potential to be a curative option for these patients.” The open-label, multicenter Phase 1 study (JSP-CP-003) is evaluating the safety, tolerability and efficacy of adding JSP191 to the standard conditioning regimen of low-dose radiation and fludarabine among patients age 65 to 74 years with MDS or AML undergoing hematopoietic cell transplantation. Patients were ineligible for full myeloablative conditioning. The primary outcome measure of the study is the safety and tolerability of JSP191 as a conditioning regimen up to one year following a donor cell transplant. “We designed JSP191 to be given as outpatient conditioning and to have both the efficacy and safety profile required for use in newborn patients and older patients for successful outcomes,” said Wendy Pang, M.D., Ph.D. Executive Director, Research and Translational Medicine, of Jasper Therapeutics. “We are enthusiastic about the reduction of measurable residual disease seen in these patients, especially given that it is associated with improved relapse-free survival. We are excited to continue our research in MDS/AML, with plans for an expanded study. We are evaluating JSP191, the only antibody of its kind, in two ongoing clinical studies and are encouraged by the positive clinical data seen to date.” About MDS and AML Myelodysplastic syndromes (MDS) are a group of disorders in which immature blood-forming cells in the bone marrow become abnormal and do not make new blood cells or make defective blood cells, leading to low numbers of normal blood cells, especially red blood cells. 1 In about one in three patients, MDS can progress to acute myeloid leukemia (AML), a rapidly progressing cancer of the bone marrow cells. 1 Both are diseases of the elderly with high mortality. Each year, about 5,000 patients with MDS and 8,000 people with AML in the G7 countries receive hematopoietic cell transplants. These transplants are curative but are underused due to the toxicity of the current high-intensity conditioning regimen, which includes the chemotherapy agents busulfan and fludarabine. About JSP191 JSP191 (formerly AMG 191) is a first-in-class humanized monoclonal antibody in clinical development as a conditioning agent that clears hematopoietic stem cells from bone marrow. JSP191 binds to human CD117, a receptor for stem cell factor (SCF) that is expressed on the surface of hematopoietic stem and progenitor cells. The interaction of SCF and CD117 is required for stem cells to survive. JSP191 blocks SCF from binding to CD117 and disrupts critical survival signals, causing the stem cells to undergo cell death and creating an empty space in the bone marrow for donor or gene-corrected transplanted stem cells to engraft. Preclinical studies have shown that JSP191 as a single agent safely depletes normal and diseased hematopoietic stem cells, including in animal models of SCID, myelodysplastic syndromes (MDS) and sickle cell disease (SCD). Treatment with JSP191 creates the space needed for transplanted normal donor or gene-corrected hematopoietic stem cells to successfully engraft in the host bone marrow. To date, JSP191 has been evaluated in more than 90 healthy volunteers and patients. JSP191 is currently being evaluated in two separate clinical studies in hematopoietic cell transplantation. A Phase 1/2 dose-escalation and expansion trial is evaluating JSP191 as a sole conditioning agent to achieve donor stem cell engraftment in patients undergoing hematopoietic cell transplantation for severe combined immunodeficiency (SCID), which is potentially curable only by this type of treatment. Data presented at the 62nd American Society of Hematology (ASH) Annual Meeting showed that a single dose of JSP191 administered prior to stem cell transplantation in a 6-month-old infant was effective in establishing sustained donor chimerism followed by development of B, T and NK immune cells. No treatment-related adverse events were reported. A Phase 1 clinical study is evaluating JSP191 in combination with another low-intensity conditioning regimen in patients with MDS or AML undergoing hematopoietic cell transplantation. For more information about the design of these two ongoing clinical trials, visit www.clinicaltrials.gov (NCT02963064 and NCT04429191). Additional studies are planned to advance JSP191 as a conditioning agent for patients with other rare and ultra-rare monogenic disorders and autoimmune diseases. About Jasper Therapeutics Jasper Therapeutics is a biotechnology company focused on the development of novel curative therapies based on the biology of the hematopoietic stem cell. The company’s lead compound, JSP191, is in clinical development as a conditioning antibody that clears hematopoietic stem cells from bone marrow in patients undergoing a hematopoietic cell transplant. This first-in-class conditioning antibody is designed to enable safer and more effective curative hematopoietic cell transplants and gene therapies. For more information, please visit us at jaspertherapeutics.com. 1https://www.cancer.org/cancer/myelodysplastic-syndrome/about/what-is-mds.html View source version on businesswire.com:https://www.businesswire.com/news/home/20210208005212/en/ CONTACT: Lily Eng W2O 206-661-8627 [email protected] Mahal Jasper Therapeutics 650-549-1403 [email protected] KEYWORD: UNITED STATES NORTH AMERICA CALIFORNIA INDUSTRY KEYWORD: ONCOLOGY HEALTH STEM CELLS GENETICS CLINICAL TRIALS BIOTECHNOLOGY SOURCE: Jasper Therapeutics, Inc. Copyright Business Wire 2021. 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Top StoriesSC Asks Centre To Pass Orders To States/UTs Ensure Payment Of Salaries To Healthworkers [Read Order] Sanya Talwar16 Jun 2020 10:56 PMShare This – xThe Supreme Court on Wednesday directed the Centre to pass appropriate directions under the Disaster Management Act to the Chief Secretaries of all States/Union Territories to ensure that directions for payment of salaries to doctors and health workers are complied with.Solicitor General Tushar Mehta told the bench that non-payment of salary will attract penal consequences under the…Your free access to Live Law has expiredTo read the article, get a premium account.Your Subscription Supports Independent JournalismSubscription starts from ₹ 599+GST (For 6 Months)View PlansPremium account gives you:Unlimited access to Live Law Archives, Weekly/Monthly Digest, Exclusive Notifications, Comments.Reading experience of Ad Free Version, Petition Copies, Judgement/Order Copies.Subscribe NowAlready a subscriber?LoginThe Supreme Court on Wednesday directed the Centre to pass appropriate directions under the Disaster Management Act to the Chief Secretaries of all States/Union Territories to ensure that directions for payment of salaries to doctors and health workers are complied with.Solicitor General Tushar Mehta told the bench that non-payment of salary will attract penal consequences under the National Disaster Management Act in terms of the notification of the Centre. The Court ordered that appropriate orders in this regard may be passed tomorrow itsefThe Court also ordered that quarantine facilities for doctors and healthworkers shall be ensured, even if they are not falling within the ‘high risk exposure’ category. Directorate of Health has been directed to ensure this by tomorrow.This was after the bench noticed that the Centre’s notification dealt with quarantine only for those health workers coming under the ambit of “high risk exposure”. The SG also informed the bench that many 5-star hotels have already been requisitioned for conversion as quarantine centres.Senior Advocate KV Vishwanathan, appearing for the petitioner Arushi Jain, urged the Court to pass directions to ensure accountability from the State Governments in the matter of payment of salaries to doctors and healthcare workers.The bench will consider the matter after four weeks to take stock of compliance. A bench of Justices Ashok Bhushan, Sanjay Kishan Kaul & MR Shah passed the directions in a plea filed by Udaipur-based lawyer Arushi Jain seeking suitable accommodation and quarantine facilities for medical workers who are involved in treating of COVID-19 patients.On June 12, basis the submission of Senior Advocate KV Vishwanathan regarding acquisition of premises in terms of the Disaster Management Act, 2005, for the setting up of proper accommodation, the Bench directed the petitioners to hand over their suggestions/concerns to the Ministry of Health and Family Welfare. The court had listed the matter for today thereafter.Further to this, top Court had slammed the government for adopting a lackadaisical approach towards providing accommodation facilities to doctors and health workers at the frontline of Coronavirus crisis. The court also took note of the denial and withholding of their remuneration, directing the Petitioner to convey their suggestions/concerns to the Ministry of Health and Family Welfare.The bench had stated orally,”We cannot have dissatisfied soldiers in this COVID war. The doctors are not being paid, these things are coming to light, what is this?” In response to the plea an Affidavit had been filed by the Ministry of Health and Family Welfare, wherein it was submitted that though adequate measures and substantive efforts (for instance, 5-star hotels being used for accommodations for doctors) had been taken by the Government, the final responsibility to protect oneself lay with the doctors themselves.The Bench, while responding that they had just received the Affidavit, stated that two aspects had to be considered:”1. How to solve this problem of high risk exposure (for doctors handling COVID patients).2. Accommodations for doctors with requisite parameters to curb the issues.”In her PIL, Dr. Jain had drawn the attention of the Court towards certain disturbing news articles coming from all across the country regarding the “harsh, deplorable and hard living conditions of doctors, nurses and support staff who are in the forefront for treating the patients suffering from Covid-19.”Click here to download orderRead OrderSubscribe to LiveLaw, enjoy Ad free version and other unlimited features, just INR 599 Click here to Subscribe. All payment options available.loading….Next Story